BP204T. PATHOPHYSIOLOGY Books : PharmaLite.in



All books are given below after syllabus



Basic principles of Cell injury and Adaptation: 

Introduction, definitions, Homeostasis, Components and Types of Feedback systems, 

Causes of cellular injury, Pathogenesis (Cell membrane damage, Mitochondrial damage, Ribosome damage, Nuclear damage), Morphology of cell injury – Adaptive changes (Atrophy, Hypertrophy, hyperplasia, Metaplasia, Dysplasia), Cell swelling, Intra cellular accumulation, Calcification, Enzyme leakage and Cell Death Acidosis & Alkalosis, Electrolyte imbalance. 

Basic mechanism involved in the process of inflammation and repair: 

Introduction, Clinical signs of inflammation, Different types of Inflammation, Mechanism of Inflammation – Alteration in vascular permeability and blood flow, migration of WBC’s, Mediators of inflammation, Basic principles of wound healing in the skin, Pathophysiology of Atherosclerosis. 



Cardiovascular System: Hypertension, congestive heart failure, ischemic heart disease (angina, myocardial infarction, atherosclerosis and arteriosclerosis) 

Respiratory system: Asthma, Chronic obstructive airways diseases. Renal system: Acute and chronic renal failure. 



Hematological Diseases: Iron deficiency, megaloblastic anemia (Vitamin B12 and folic acid), sickle cell anemia, thalassemia, hereditary acquired anemia, hemophilia. 

Endocrine system: Diabetes, thyroid diseases, disorders of sex hormones. 

Nervous system: Epilepsy, Parkinson’s disease, stroke, psychiatric disorders: depression, schizophrenia and Alzheimer’s disease. 

Gastrointestinal system: Peptic Ulcer. 


Inflammatory bowel diseases, jaundice, hepatitis (A, B, C, D, E, F) alcoholic liver disease. 

Disease of bones and joints: Rheumatoid arthritis, osteoporosis and gout. Principles of cancer: classification, etiology and pathogenesis of cancer. 



Infectious diseases: Meningitis, Typhoid, Leprosy, Tuberculosis, Urinary tract infections.  Sexually transmitted diseases: AIDS, Syphilis, Gonorrhea. 


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