BP204T. PATHOPHYSIOLOGY Books
All books are given below after syllabus
Unit-I
Basic principles of Cell injury and Adaptation:
Introduction, definitions, Homeostasis, Components and Types of Feedback systems,
Causes of cellular injury, Pathogenesis (Cell membrane damage, Mitochondrial damage, Ribosome damage, Nuclear damage), Morphology of cell injury – Adaptive changes (Atrophy, Hypertrophy, hyperplasia, Metaplasia, Dysplasia), Cell swelling, Intra cellular accumulation, Calcification, Enzyme leakage and Cell Death Acidosis & Alkalosis, Electrolyte imbalance.
Basic mechanism involved in the process of inflammation and repair:
Introduction, Clinical signs of inflammation, Different types of Inflammation, Mechanism of Inflammation – Alteration in vascular permeability and blood flow, migration of WBC’s, Mediators of inflammation, Basic principles of wound healing in the skin, Pathophysiology of Atherosclerosis.
Unit-II
Cardiovascular System: Hypertension, congestive heart failure, ischemic heart disease (angina, myocardial infarction, atherosclerosis and arteriosclerosis)
Respiratory system: Asthma, Chronic obstructive airways diseases. Renal system: Acute and chronic renal failure.
Unit-III
Hematological Diseases: Iron deficiency, megaloblastic anemia (Vitamin B12 and folic acid), sickle cell anemia, thalassemia, hereditary acquired anemia, hemophilia.
Endocrine system: Diabetes, thyroid diseases, disorders of sex hormones.
Nervous system: Epilepsy, Parkinson’s disease, stroke, psychiatric disorders: depression, schizophrenia and Alzheimer’s disease.
Gastrointestinal system: Peptic Ulcer.
Unit-IV
Inflammatory bowel diseases, jaundice, hepatitis (A, B, C, D, E, F) alcoholic liver disease.
Disease of bones and joints: Rheumatoid arthritis, osteoporosis and gout. Principles of cancer: classification, etiology and pathogenesis of cancer.
Unit-V
Infectious diseases: Meningitis, Typhoid, Leprosy, Tuberculosis, Urinary tract infections. Sexually transmitted diseases: AIDS, Syphilis, Gonorrhea.
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