BP501T. MEDICINAL CHEMISTRY – II Books : PharmaLite.in



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"Study of   the development of   the following classes of   drugs, Classification, mechanism of action, uses of drugs mentioned in the course, Structure activity relationship of selective class of drugs as specified in the course and synthesis of drugs superscripted (*)" 



Antihistaminic agents:   Histamine, receptors   and   their   distribution   in   the human body. 

H1–antagonist: Diphenhydramine hydrochloride*, Dimenhydrinate, Doxylamine  succinate,  Clemastine  fumarate,  Diphenylpyraline hydrochloride, Triphelenamine hydrochloride, Chlorcyclizine hydrochloride, Meclizine hydrochloride,  Buclizine  hydrochloride,  Chlorpheniramine maleate,  Triprolidine hydrochloride*,  Phenidamine  tartrate,  Promethazine  hydrochloride*, Trimeprazine  tartrate,  Cyproheptadine  hydrochloride,  Azatidine  maleate, Astemizole, Loratadine, Cetirizine, Levocetrizine Cromolyn sodium. 

H2-antagonists: Cimetidine*, Famotidine, Ranitidine. 

Gastric proton-pump inhibitors: Omeprazole, Lansoprazole, Rabeprazole, Pantoprazole. 

Anti-neoplastic agents: 

Alkylating     agents: Meclorethamine*, Cyclophosphamide, Melphalan,  Chlorambucil, Busulfan, Thiotepa. 

Antimetabolites: Mercaptopurine*, Thioguanine, Fluorouracil, Floxuridine, Cytarabine, Methotrexate*, Azathioprine. 

Antibiotics: Dactinomycin, Daunorubicin, Doxorubicin, Bleomycin.  

Plant products: Etoposide, Vinblastine sulphate, Vincristine sulphate. Miscellaneous: Cisplatin, Mitotane. 



Anti-anginal: Vasodilators: Amyl Nitrite, Nitroglycerin*, Pentaerythritol tetranitrate, Isosorbide dinitrite*, Dipyridamole. 

Calcium   channel   blockers:   Verapamil, Bepridil   hydrochloride, Diltiazem hydrochloride, Nifedipine, Amlodipine, Felodipine, Nicardipine, Nimodipine. 

Diuretics: Carbonic Anhydrase Inhibitors: Acetazolamide*, Methazolamide, Dichlorphenamide. 

Thiazides: Chlorthiazide*, Hydrochlorothiazide, Hydroflumethiazide, Cyclothiazide, Loop Diuretics: Furosemide*, Bumetanide, Ethacrynic acid. 

Potassium sparing Diuretics: Spironolactone, Triamterene, Amiloride. Osmotic Diuretics: Mannitol. 

Anti-hypertensive Agents: Timolol, Captopril, Lisinopril, Enalapril, Benazepril hydrochloride, Quinapril Hydrochloride, Methyldopate Hydrochloride* Clonidine hydrochloride, Guanethidine Monosulphate, Guanabenz Acetate, Sodium Nitroprusside, Diazoxide, Minoxidil, Reserpine, Hydralazine hydrochloride. 


Anti-arrhythmic Drugs: Quinidine Sulphate, Procainamide Hydrochloride, Disopyramide Phosphate*, Phenytoin Sodium, Lidocaine Hydrochloride, Tocainide Hydrochloride, Mexiletine Hydrochloride, Lorcainide Hydrochloride, Amiodarone, Sotalol. 

Anti-hyperlipidemic   agents: Clofibrate, Lovastatin, Cholestyramine and Colestipol. Coagulant & Anticoagulants: Menadione, Acetomenadione, Warfarin*, Anisindione, Clopidogrel. 

Drugs used in Congestive Heart Failure: Digoxin, Digitoxin, Nesiritide, Bosentan, Tezosentan. 


Drugs acting on Endocrine system: Nomenclature, Stereochemistry and metabolism of steroids. 

Sex hormones:  Testosterone, Andralone, Progestrones, Oestriol, Oestradiol, Oestrione, Diethyl Stilbestrol. 

Drugs for erectile dysfunction: Sildenafil, Tadalafil. 

Oral contraceptives: Mifepristone, Norgestrel, Levonorgestrel 

Corticosteroids: Cortisone, Hydrocortisone, Prednisolone, Betamethasone, Dexamethasone. 

Thyroid and antithyroid drugs: L-Thyroxine, L-Thyronine, Propylthiouracil, Methimazole. 


Antidiabetic agents: Insulin and its preparations. 

Sulfonylureas: Tolbutamide*, Chlorpropamide, Glipizide, Glimepiride.  

Biguanides: Metformin. 

Thiazolidinediones: Pioglitazone, Rosiglitazone, Meglitinides, Repaglinide, Nateglinide.  

Glucosidase inhibitors: Acarbose, Voglibose. 

Local Anesthetics: SAR of Local anesthetics. 

Benzoic acid derivatives; Cocaine, Hexylcaine, Meprylcaine, Cyclomethycaine, Piperocaine. 

Amino Benzoic acid derivatives: Benzocaine*, Butamben, Procaine*, Butacaine, Propoxycaine, Tetracaine, Benoxinate. 

Lidocaine/Anilide derivatives: Lignocaine, Mepivacaine, Prilocaine, Etidocaine. Miscellaneous: Phenacaine, Diperodon, Dibucaine.


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